Book of annotations contains the main ideas presented in the reports of the participants of the 10th International Vanquard Science Congress "The Scientific Paradigm of 21st Century Civilization: Capitalism, Socialism and the 4th Technological Revolution of Mankind", held October 17-19, 2018 in Chelyabinsk State University. A total of 109 applications and annotations were received from participants from 13 countries. The book contains more than 30 reports in a foreign languages. More than 50 reports of participants are presented by teachers, students and staff of Chelyabinsk State University.